Office space for lease Hamilton. Welcome to 201 James Street South, professional private offices located in the heart of Hamilton. We have an array of offices to choose from ranging from 116 sf to 710 sf distributed over 3 floors. The building is located south of the Hamilton GO station, is on a major transit route, is surrounded by parking and incoming major developments. Amenities in the area include St. Joseph's Hospital, well established restaurants, retail and entertainment centers. Ideal for professional office, personal services and ecommerce. All utilities are included. The office is ready to move in. Book your appointment today! Monthly net lease rate and TMI vary by suite. See individual suite listings for more information.